Biomechanics in health and disease:
advanced physical tools for innovative early diagnosis
H2020-MSCA-ITN-2018 n. 812772

ESR3. Harinderbir Kaur

Harinderbir Kaur Short biographic note

A graduate in Biomedical engineering, from India. During my graduate internships I worked in various multi-specialty hospitals.  I learned principal and working of various medical devices along with its handling and care. My first master’s is in Instrumentation engineering at Panjab University, India. It gave me an insight to various analytical instrumentation techniques for example, SEM,TEM, XRD, chromatography . My second master’s was in Nanomedicine and structural biology from INP Phelma, France. Here, during my internship I studied elasticity of plant root cells with a specialization in atomic force spectroscopy technique. 

AS an ESR 3, I will be responsible to perform rigorous indentation measurements on plant root tissues to detect early events in growth arrest due to environmental stress. The position as an ESR in Phys2BioMed MSCA-ITN-ETN will give me an opportunity to get myself acquainted with finer nuances of research and development. 

Useful links:

E-mail: harinderbir.kaur@ibs.fr

 

Project Title

Nano-mechanical response in stressed and diseased living root tissues

Start date

1st June 2019

Beneficiary

CEA

Objectives

Perform rigorous indentation measurements on plant root tissues to detect early events in growth arrest due to environmental stress.

Expected results

Nano-mechanical response of root tissues during abiotic stress for understanding the STOP1-LPR1 multi-stress signaling pathways of Arabidopsis. The ESR will perform nano-mechanical measurements of cells on live tissues (roots). Measurements will be performed on wild-type and mutant plants both in normal and stress conditions. The ESR will be engaged in all work packages and will participate to communication and dissemination.

Planned secondments

1. BioMeca, P. Milani (1 month, month 8). Testing new scripting tools for mechanical measurements; 2. UB, M. Radmacher (1 month, month 12) Comparing data analysis; 3. IBEC, D. Navajas (3 months, month 15) Mastering mechanical measurements on decellularized lung tissue; 4. INSERM, F. Rico (3 months, month 22) Participating in shaping raw data databases for cross-laboratory analysis; 5. O11, D. Iannuzzi (1 month, month 28) Compare experimental mechanical measures on tissues using industrial partner nano-indenter; 6. Vmicro, B. Walter, (1 month, month 29) Compare experimental mechanical measures on tissues using industrial partner vertical cantilevers.

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